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Phth-NO-dPEG™(4)-NHS
Chemical name: 1-Phthalimidoxy-3,6,9,12-tetraoxapentadecan-15-oic acid succinimdyl ester // Synonyms: Phthaloyl-PEG(4)-NHS, 2,5-dioxopyrrolidin-1-yl 1-(1,3-dioxoisoindolin-2-yloxy)-3,6,9,12-tetraoxapentadecan-15-oate
- Product code:PEG5080
- Formula:C23H28N2O11
- Molecular weight:508.48 g/mol
Starting at €220.00
description
Spacer length 17 atoms or 19.0 A.
PEG reagent, which forms stable oxime conjugates useful in formation of glycolconjugates with oligonucleotides or protein-polysaccaride conjugates.
references
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag; PNAS 2009; 106: 3000-3005.
Site-Specific Modification of Recombinant Proteins: A Novel Platform for Modifying Glycoproteins Expressed in E. coli; G.E. Hendersen, K.D. Isett, T.U. Gerngross; Bioconjugate Chemistry 2011; 22: 903-912.
Synthesis of Oligonucleotide Glycoconjugates Inside a Glass Capillary through Oximation Ligations; Bioconjugate Chemistry 2010; 21: 748-755.
Efficient Surface Patterning of Oligonucleotide Glycoconjugates Inside a Glass Capillary through Oxime Bond Formation; N. Dendane, A. Hoang, L. Guillard, E. Defrancq, F. Vinet. P. Dumy; Bioconjugate Chemistry 2007; 18: 671-676.
Versatile and efficient synthesis of protein-polysaccharide conjugate vaccines using aminooxy reagents and oxime chemistry; A. Lees, G. Sen, A. Lopez Acosta; Vaccine 2006; 24: 716-729.
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