Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Quick contact
Please send me more information about
Biotin-Pen-CBT
Chemical name: N-(5-((2-cyano-6-benzothiazolyl)amino)-5-oxopentyl)-biotin // Synonyms: N-(2-cyanobenzo[d]thiazol-6-yl)-5-biotinyl-pentanamide, CBT-pentanoyl-biotin, Biotin-pentanoyl-CBT, Biotin-pentanoyl-cyanobenzothiazole, Biotin-C5-CBT, BPCBT, CBTP-Biotin
- Product code:RL-4240
- CAS No.:2550397-17-4
- Formula:C23H28N6O3S2
- Molecular weight:500.64 g/mol
Starting at €200.00
description
The site-specific labeling of proteins by chemical reactions has gained increased interest for the investigation of cellular processes. In this regard, the CBT-Cys „click“ condensation reaction has found wide applicability in recent years. The reaction is highly biocompatible and controllable and runs under physiological conditions. It is based on the condensation between an N-terminal L- or D-Cysteine with the cyano group of CBT.
references
N, S-Double Labeling of N-Terminal Cysteines via an Alternative Conjugation Pathway with 2-Cyanobenzothiazole; W. Wang, J. Gao; J. Org. Chem. 2020, 85(3): 1756–1763. https://doi.org/10.1021/acs.joc.9b02959
Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV-2; J. T. Hampton, T. J. Lalonde, J. M. Tharp, Y. Kurra, Y. R. Alugubelli, C. M. Roundy, G. L. Hamer, S. Xu, W. R. Liu; ACS Chem. Biol. 2022, 17(10): 2911–2922. https://doi.org/10.1021/acschembio.2c00565
Bulk or large quantity order?
Do you need larger quantities for your development or production?
Do you need further information about this product?
get in contact
Related Products
Broschures & Flyers
Related news
-
News Amino Acids Life Sciences Product FocusCyanobenzothiazole (CBT) Derivatives for “Click” Conjugation
Discover the cyanobenzothiazole (CBT) click reaction, a not (yet) so well-known biocompatible and bio-orthogonal mechanism faster
view details
We found other products you might like!
