Articles by tag "brochure"

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  1. Polymers Enlarge the Potential of Biopharmaceuticals Introduction The Biopharmaceuticals market, estimated at US$ 200 billion globally in 2013 by reportbuyer.com (Biopharmaceuticals - A Global Market Overview, 2013, London), is further projected to reach US$ 500 billion by 2020, growing at 13.5 % CAGR between 2010 and 2020. Among different ...
  2. Pharmacological Effects of Polymer Therapeutics 1. Basics and Principles of Polymer Therapeutics 1.1 Pharmacological Effects Small drug molecules and also large biomolecules like proteins or antibodies suffer rapid clearance from human body. The concentration of the drug compound drops rapidly as it is removed from the body. Treatment ...
  3. Polydispersity of Polymer Carriers 1.2 Polydispersity The polymers in this context are a polymeric linear structures with n repeating units of monomers. Depending whether the polymer is consisting of one single molecular weight (only one n existing) or of a range of compounds with an average mass and a distribution of n ...
  4. Comparison of Carriers for Polymer Therapeutics 1.2 Polydispersity The polymers in this context are a polymeric linear structures with n repeating units of monomers. Depending whether the polymer is consisting of one single molecular weight (only one n existing) or of a range of compounds with an average mass and a distribution of n ...
  5. Poly(Glutamic Acid) as Versatile Biodegradable Drug Carrier Polyglutamates are well known to be highly biocompatible, biodegradable and multifunctional polymers, which have already been used as building blocks in polymer drug conjugates and polymeric micelles. Those systems have been utilized for various medical applications ranging from therapy to ...
  6. Polysarcosine – a True Alternative to PEG 2.4 Polysarcosine – a True Alternative to PEG The PEGylation technology has transformed the fields of bioconjugation, drug delivery and nanomedicine tremendously. PEGylation of surfaces, drugs and biologics has become a multi-billion euro business. However, a heavily crowded patent ...
  7. Poly(Ethylene Glycol) – the Pioneer in Polymer Therapeutics 3. Poly(ethylene glycol) – the Pioneer in Polymer Therapeutics PEGs show a spectrum of unique physical and chemical properties, which have been described in literature extensively by the pioneers in PEGylation: Harris, Veronese and recently by Hermanson. Here are summarized the most ...
  8. Amino-PEG-Acids and their Active Esters 3.2 Amino-PEG-Acids and Active Esters PEGylation modification with PEG carboxylic acids or PEG active esters is useful for improving water solubility, increasing chemical stability, decreasing aggregation and toxicity, and reduction of immunogenicity. Amino protected amino-PEG-acids can be ...
  9. Lipoamide-PEGs Confer Extra Strong Binding 3.7 PEG-Thiols 3.7.1 Lipoamide-PEGs Nanotechnology and nanobiotechnology using gold or silver particles, quantum dots or even magnetic particles are broadly diverse, rapidly expanding areas of study in medical diagnostics and therapeutics, sensoric and chemistry. Metal ...
  10. Mercapto-PEG-Acids for Bioconjugation 3.7.2 Mercapto-PEG-Acids S-Acetyl-PEG-acids and active esters provide a method for converting amino groups to a thiol, while incorporating PEG units. Conjugation with thiol reactive agents e.g., maleimides, vinyl sulfones or α-halo keto functionalized reaction partners increases the ...
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Items 1 - 10 of 17 total