Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Währung
EUR
Schneller Kontakt
Bitte senden Sie mir mehr Informationen über
Orexin A
Chemischer Name: Orexin A (human, bovine, canine, mouse, ovine, porcine, rat) acetate salt; Sequence: [Cys4-Cys12,Cys7-Cys14] pEPLPDCCRQKTCSCRLYELLHGAGNHAAGILTL-NH2 acetate salt // Synonyme: Hypocretin-1 (human, bovine, canine, mouse, ovine, porcine, rat)
- Art-Nr.:LS-3520
- CAS Nr.:205640-90-0
- Formel:C152H243N47O44S4
- Molare Masse:3561,16 g/mol
Startet von auf Anfrage
description
Orexin A (hypocretin-1) is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of orexin A to rats stimulated food consumption in a dose-dependent manner. The effect persisted at 4 h after injection, as orexin A seems to be resistant to peptidases. Orexin A specifically binds a G protein-coupled receptor, OX1R (IC50 = 20 nM to displace 50 % of radiolabeled orexin A bound to this receptor). Orexin A produced in the amygdala induces wakefulness and plays a role in the induction of human emotions. Narcolepsy has been associated with orexin deficiency.
references
A.M.Blouin et al.; Nat. Commun. 2013; 4: 1547.
E.Göncz et al.; Endocrinology 2008; 149: 1618.
M.R.Jain et al.; Regul. Peptides 2000; 87: 19.
T.Sakurai et al.; Cell 1998; 92: 573.
M.W.Schwartz; Nat. Med. 1998; 4: 385.
Bulk oder Großmengen-Bestellung?
Sie benötigen größere Mengen für Ihre Entwicklung oder Produktion?
Benötigen Sie weitere Informationen über dieses Produkt?
kontaktieren Sie uns
Verwandte Produkte
![Structure image for E[c(RGDfK)]c(RGDfK)](https://www.iris-biotech.de/media/catalog/product/L/S/LS-3980.svg?width=240&height=140&store=de&image-type=small_image)
![Structure image for ICG-E[c(RGDfK)]2](https://www.iris-biotech.de/media/catalog/product/L/S/LS-3950.svg?width=240&height=140&store=de&image-type=small_image)
![Structure image for cyclo-[RGDfK(TPP)]](https://www.iris-biotech.de/media/catalog/product/L/S/LS-3920.svg?width=240&height=140&store=de&image-type=small_image)
Produkte, die Sie auch interessieren könnten!
![Structure image for cyclo-[RGDfK(TPP)]](https://www.iris-biotech.de/media/catalog/product/L/S/LS-3920.svg?width=216&height=140&store=de&image-type=small_image)
![Structure image for ICG-E[c(RGDfK)]2](https://www.iris-biotech.de/media/catalog/product/L/S/LS-3950.svg?width=216&height=140&store=de&image-type=small_image)
![Structure image for E[c(RGDfK)]c(RGDfK)](https://www.iris-biotech.de/media/catalog/product/L/S/LS-3980.svg?width=216&height=140&store=de&image-type=small_image)
