Superior Performance at a Sensational Price!

• Homologous line of Dyes (λ_exc = 550 / 647 / 747 nm) differing only in length of polymethine bridge.
• Identical linker & coupling chemistry at each WL.
• Available as –COOH, -NHS, -Maleimide, -Alkyne, -Azide
• Half the price of other well-known dyes like Alexa- & Cy-Dyes.
• Available also in large quantities.
• Broadly applied in cell imaging, FRET, fluorescence quenching.
• Quality made in Germany.
• Customized production according to individual needs possible.

Our innovative MiDyes are carbocyanine fluorophores (analog of Cy-Dyes) available also in larger quantities at a sensational price. Save 50% and more compared to competitor’s labels like Alexa- and Cy-Dyes. MiDyes are available with three different excitation wavelengths (550 / 647 / 747 nm) differing only in the length of the polymethine bridge. This homologous line of dyes ensures identical behaviour and thus good comparability of differently colored labels.
MiDyes have proven their suitability in numerous applications such as protein-, peptide- and oligo- labeling, cell- and animal imaging, FRET and fluorescence quenching. They are stable both under aqueous buffer and solid phase synthesis conditions.
All our MiDyes are available with five functional groups: Carboxylic Acid, Succinimidyl Ester, Maleimides, Azides and Alkynes for almost any kind of biolabeling reaction.

Our specialists can also construct a customized MiDyes adapted to your special requirements.
Don’t hesitate to contact us!

Find more details about MiDye properties and applications in literature:

• Sisson A.L: et al., Biocompatible Functionalized Polyglycerol Microgels with Cell Penetrating Properties. Angew. Chem. Int. Ed. 2009; 48: 7540–7545; DOI: 10.1002/anie.200901583.
• Licha K. et al., Synthesis, Characterization, and Biological Properties of Cyanine-Labeled Somatostatin Analogues as Receptor-Targeted Fluorescent Probes. Bioconjugate Chem. 2001; 12: 44-50.
• Licha K. et al., Optical molecular imaging of lymph nodes using a targeted vascular contrast agent. Journal of Biomedical Optics 2005; 10(4): 041205.
• Bhargava S. et al., A complete substitutional analysis of VIP for better tumor imaging properties. J. Mol. Recognit. 2002; 15: 145–153; DOI:10.1002/jmr.565.
• Klohs J. et al., Near-infrared fluorescence imaging with fluorescently labeled albumin: A novel method for non-invasive optical imaging of blood–brain barrier impairment after focal cerebral ischemia in mice. Journal of Neuroscience Methods 2009; 180(1):126-32.
• Becker A. et al., Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands. nature biotechnology 2001; 19: 327- 331.
• Ebert B. et al., Cyanine dyes as contrast agents for near-infrared imaging in vivo: acute tolerance, pharmacokinetics, and fluorescence imaging. J. Biomed. Opt. 2011; 16(6): 066003; DOI:10.1117/1.3585678
• Socher E. et al., Dual fluorophore PNA FIT-probes--extremely responsive and bright hybridization probes for the sensitive detection of DNA and RNA. Org Biomol Chem. 2012; 10(36):7363-71. doi: 10.1039/c2ob25925g.