Visit this regularly updated section to check out the latest additions to our portfolio, as well as the latest developments at Iris Biotech.

  1. Fmoc-Amox, A Novel Reagent for Fmoc-Protection

    The most common reagent for the Fmoc-protection of amino acids is currently Fmoc-OSu, followed by Fmoc-Cl. However, the use of these reagents is usually accompanied by several side reactions, such as the formation of beta-alanine and dipeptides. read more
  2. Fmoc-L-Cys(Propargyl)-OH

    This alkyne-functionalized cysteine building block can be incorporated into peptides via the Fmoc strategy. read more
  3. Fmoc Deprotection Reagents

    The Fmoc group is the most frequently used protecting group in peptide chemistry. The most common deprotection conditions involve a solution of 20% piperidine in DMF.

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  4. Standard Fmoc Amino Acid Building Blocks

    Amino acids of high quality are crucial for the synthesis of peptides with a high purity.

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  5. Coupling Reagents for Peptide Chemistry

    In this news section, we highlight three useful coupling reagents for peptide chemistry: PyCLOCK, PyAOP and HDMA.

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  6. Triamino Acids

    Fmoc-L-Dap(2-Boc-aminoethyl)-OH is the first in a series of new triamino acid building blocks. This azalysine is useful for introducing positive charges into a peptide, or for creating branched structures.

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  7. Building Blocks for the SPPS of FRET-based fluorogenic protease substrates

    The classic FRET pair EDANS and DABCYL is now available linked to Fmoc amino acid building blocks that can be readily used in SPPS. Conveniently synthesize your own custom protease substrates!

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  8. The Safety-Catch Acid-Labile (SCAL)-Linker

    The SCAL linker offers superior chemical stability and permits a variety of orthogonal solid-phase approaches. It is fully compatible with the Fmoc-, Boc- and Alloc- strategies. Cleavage can be performed either by a simultaneous, or by a two-step reduction/acidolysis procedure to afford peptide amides.

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  9. New Iris Kits for the Synthesis of Peptoids and N-Alkylated Peptides

    Peptides as pharmaceutical compounds suffer from unfavorable pharmacokinetics which is, among other things, due to a slow uptake into cells and rapid proteolytic cleavage. N-Alkylation of peptides is a valuable tool to overcome these limitations. We now offer new kits that enable the facile preparation of peptoids and N-alkylated peptides.

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  10. Chlorotoxin & Biotin-Chlorotoxin

    Chlorotoxin is a chloride channel blocker which has been found in the venom of the Egyptian scorpionLeiurus quinquestriatus. read more

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