Drug Metabolism

Drug Metabolism

Nonpolar toxic substances, drugs, but also natural substances, like steroids are often glucuronidated to be excreted out of the body.

Find here glucuronides of many drugs that are secreted via this pathway. Many drug-drug interactions are caused by drugs affecting the activity of drug metabolizing CYP enzymes. For monitoring the effects on those enzymes, we provide harmane derivatives as a superior class of high turnover CYP substrates.