Biocatalysis

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  1. Understanding enzyme immobilisation Ulf Hanefeld, Lucia Gardossi and Edmond Magner Chem. Soc. Rev.2009; 38:453–468; DOI: 10.1039/b711564b Abstract:Enzymes are versatile catalysts in the laboratory and on an industrial scale. To broaden their applicability in the laboratory and to ensure their (re)use in manufacturing the ...
  2. A Three-Dimensional Quanititative Structure-Activity Relationship (3D-QSAR) Model for Predicting the Enantioselectivity of Candida antarctica Lipase B Paolo Braiuca, Knapic Lorena, Valerio Ferrario, Cynthia Ebert, and Lucia Gardossi Adv. Synth. Catal.2009; 351:1293 – 1302 Abstract:Computational techniques involving molecular modeling coupled with multivariate statistical analysis were used to evaluate and predict quantitatively the ...
  3. Preparation of D-amino acids by enzymatic kinetic resolution using a mutant of penicillin-G acylase from E. coli Chiara Carboni, Hans G. T. Kierkels, Lucia Gardossi, Kamil Tamiola, Dick B. Janssen and Peter J. L. M. Quaedflieg Tetrahedron Asymmetry2006; 17:245–251 Abstract: We have demonstrated for the first time that D-glutamine (D-Gln) and D-glutamic acid (D-Glu) can be efficiently obtained in ...
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