Boc-Val-Ala-PAB

Chemical name: t-Butyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol // Synonyms: tert-butyl (S)-1-((S)-1-(4-(hydroxymethyl)phenylamino)-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamate;N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-L-Alaninamide

  • Product code:ADC1040
  • CAS No.:1884577-99-4
  • Formula:C20H31N3O5
  • Molecular weight:393.48 g/mol

Starting at $292.50

Grouped product items
Qty Packing unit Price SKU
250 mg
$292.50
ADC1040.0250
1 g
$845.00
ADC1040.1000
Safety Data Sheets
description

Linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell.

references

Laurent Ducry (ed.), Antibody-Drug Conjugates, Methods in Molecular Biology, vol. 1045, DOI 10.1007/978-1-62703-541-5_5, # Springer Science+Business Media, LLC 2013.

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