Welcome to Iris Biotech
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Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying though a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.Continue to Iris Biotech GmbHSend request to US distributor
A new attempt to cure diseases caused by excessive expression of a certain protein is to feed this protein to the cell's Ubiquitin–Proteosome system by using proteolysis targeting chimeras (PROTACs*). These PROTACs consist of two linked protein ligands: one with high affinity for E3 ubiquitin ligase and one with high affinity for the protein of interest (POI). Recruitment of the E3 ligase to the POI causes ubiquitination and subsequent degradation of the target protein.
To construct a suitable PROTAC, we here offer a variety of E3 ubiquitin ligase ligands and their combination with linkers of various length and elective amino-, carboxyl-, mercapto- or click-reactive end (“Partial PROTACs”). Further to these pre-designed building blocks, we are happy to synthesize for you many other ligand-linker combinations or “Complete PROTACs” on custom synthesis basis.
* PROTAC is a registered trademark of Arvinas Operations, Inc. and is used under license.
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