Amino Acids

  1. Cyanobenzothiazole (CBT) Derivatives for “Click” Conjugation

    Discover the cyanobenzothiazole (CBT) click reaction, a not (yet) so well-known biocompatible and bio-orthogonal mechanism faster than the famous azide-alkyne cycloaddition (CuAAC).

    read more
  2. PotM: Safety Catch - Orthogonally Protected Amino Acids

    Add a new dimension of orthogonality to your peptide synthesis by using Safety-Catch arylalkyl sulfoxide protecting groups! This newsletter tells you about benefits and usage – Read on!

    read more
  3. Photoaffinity Labeling by Diazirine Building Blocks

    Discover our diazirine-substituted building blocks suitable for the analysis of protein-protein and RNA-protein interactions via proximity labeling upon photoactivation. Read on for more information!

    read more
  4. Carbamidomethylated Cysteine as SPPS Building Block

    Our building block Fmoc-L-Cys(Cam)-OH enables peptides resembling reduced and carbamido-methylated protein fragments by standard SPPS without error-prone modification reactions.

    read more
  5. Fatty Di-Acids

    Peptide therapeutics – fewer injections/lower doses by prolonging their half-life via addition of a lipid modification that promotes binding to serum proteins such as albumin. Read on for recent innovations!

    read more
  6. Non-canonical Tryptophan Derivatives

    Non-canonical Tryptophan analogs can help to improve your API’s performance in terms of potency, specificity, and stability. We offer various substituted Trp derivatives also available in small quantities for screening.

    read more
  7. PotM: Argpyrimidine Building Block for SPPS

    Argpyrimidine is the result of a Maillard Reaction-like nonenzymatic posttranslational modification. You want to investigate the effect of this change on function and stability? Get the building block!

    read more
  8. Acylation Efficiencies on Ser and Thr Pseudoproline Monomers

    In two joint studies together with Prof. F. Albericio we investigated the coupling efficiencies of Ser and Thr pseudoproline monomers and their use for the synthesis of inaccessible peptide sequenes. Read on!

    read more
  9. Abraligabra - Reagents and Building Blocks for Chemical Ligation

    We can’t get enough of new products and innovations! Read this blog to get detailed information on the cyanylating reagent NTCB as well as selenocysteine amino acids, both useful tools for peptide ligation.

    read more
  10. PotM: Fmoc-Ser(Msbh)-OH

    You are working on complex peptides and are looking for a new level of orthogonality facilitating the overall synthetic process and improving your yields? Check out the Msbh safety-catch protecting group!

    read more

Items 1-10 of 93

Show per page