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Building Blocks
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Azobenzene Photoswitches
Engineer shape-shifting peptides, controllable by a laser as magic wand! In this newsletter, we’ll explore the possibilities of photo switchable building blocks based on azobenzene.
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PotM: Oligomeric Sarcosine Building Blocks
You are looking for monodisperse Sarcosines? You want to use Sarcosine for SPPS? You need to improve your drug's hydrophilicity and search for PEG alternatives? Read on!
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Fluorogenic Building Blocks for Peptide Guided Wash-Free Imaging
Live-imaging of dynamic structures and catching events in living cells is a challenge, as most fluorescent probes have a high background signal. For alternatives, please read on!
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A Tetrazole-Substituted Lysine as PTM Isostere
The tetrazole isostere of malonyllysine is thermally stable and does not suffer from decarboxylation. Discover our building blocks suitable for incorporation via solid-phase peptide synthesis.
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PotM: Blockbuster Building Blocks
Are you keen on developing novel billion-dollar-selling peptide API blockbusters? Most recent ones use lipophilic Albumin binding moieties. Of course, Iris Biotech has the necessary building blocks!
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Glycosylated Asparagine Building Blocks for SPPS
Add glycans to your proteins with our ready-to-use Fmoc asparagine building blocks suitable for solid phase peptide synthesis and produce peptides with exactly defined glycosylation patterns!
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Automated Peptide Synthesis
The discovery of the Merrifield peptide synthesis paved the way for automated solid-phase peptide synthesis (SPPS) enabling fast and convenient simultaneous peptide synthesis.
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PotM: Small-sized, neutral fluorogenic amino acids suitable for SPPS
Discover our small-sized, neutral Fmoc-protected nitrobenzoselenadiazole- and nitrobenzothiadiazole-modified amino acids suitable for SPPS of fluorescent peptides.
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Peptide Nucleic Acids as Stable DNA and RNA Analogs
One molecule, two identities: PNAs are composed of nucleobases arranged on a peptidic backbone. Discover our PNA building blocks as ready-to-use bases suitable for SPPS.
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PotM: Next Generation Lysine Side Chain Protecting Groups
Sick of Lysine side chain protecting groups jumping around, yielding scrambled peptides? Check our various options to fine-tune protecting group stability vs. cleavability to optimize your peptide yield.
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