Product of the month

Herein we highlight products which we consider to be of special interest to our customers.

  1. PotM: CliCr® - an innovative click reagent

    Herein, we present CliCr® as an innovative cyclic alkyne for metal-free strain-promoted click chemistry. Read our blog for detailed information about CliCr® reagents based on TMTHSI and check out available derivatives!

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  2. PotM: His Tags for the Chemical Modification of Peptides

    Jensen et al. developed two methods that use poly-His sequences to direct the highly selective acylation of proteins, either at the N-terminus or at a specific Lys residue. Read on for more information.

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  3. PotM: Fmoc-Ser(Msbh)-OH

    You are working on complex peptides and are looking for a new level of orthogonality facilitating the overall synthetic process and improving your yields? Check out the Msbh safety-catch protecting group!

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  4. PotM: 1,4-Benzenedimethanethiol (BDMT)

    1,4-Benzenedimethanethiol is used as thiol scavenger during solid-phase peptide synthesis. In comparison to other thiol scavengers, this reagent is odorless and provides high quality crude peptides.

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  5. PotM: Smoc Amino Acids

    Herein, we present the Clean Peptide Technology using Smoc Amino Acids developed by Sulfotools in Germany. Replace organic solvents with water during peptide synthesis - Read on for more information!

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  6. PotM: Biotin – Desthiobiotin - Iminobiotin

    Herein, we present 2-Iminobiotin, a cyclic guanidino analogue of biotin with pH-dependent affinity for avidin, and compare it to biotin and desthiobiotin. Click here for more detailed information.

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  7. PotM: A Lysine Multitool Building Block

    The para-azido benzyloxycarbonyl protected lysine building block Fmoc-L-Lys(4-N3-Z)-OH (FAA8830) is useful for a wide range of applications. Read on to find out more!

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  8. PotM: Towards “Greener” Peptide Synthesis – Alternative Solvents for Loading of 2-CTC and 4-MBH-Br

    Replace undesired solvents such as DCM, THF and DMF during the loading of 2-CTC and 4-MBH-Br resin by a “greener” EtOAc/MeCN (1:1) mixture. Click here and read on for more details.

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  9. PotM: Proteolysis Targeting Chimeras (PROTACs®)

    Drug the undruggable – click here to get more information about the use of PROteolysis TArgeting Chimeras (PROTACs®) as a tool for targeted protein degradation and discover available building blocks.

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  10. PotM: Functionalized Polysarcosines for the Formation of Lipid Nanoparticles: Towards Improved RNA Delivery

    Interested in polymers for the delivery of promising drug candidates, e.g. nucleic acids? Discover our selection of lipidated polyamino acids and custom capabilities. Read on to find out more!

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