Linkerology

  1. Combination Therapy & Linkerology®

    Discover possibilities to fight chronic pain diseases by employing linker technologies. Check out the options for multiple drug conjugation in combination with different release mechanisms.

    read more
  2. Linkerology® on Metal & Ore Surfaces

    A heart of gold! Metals and ores - see here how their surfaces can be equipped with bifunctional organic linker molecules and thus be turned into modifiable biocompatible materials.

    read more
  3. PotM: Multiconjugates via Simultaneous Double-Click Reaction

    Discover our new building block 4-(azido-propyl-tetrazine)phenylalanine (pTAF) and make use of the orthogonality of the 2nd and 3rd generation Click reaction to build multiconjugates via double-Click.

    read more
  4. Conjugating Small Molecule Drugs

    You want to attach your small molecule to a certain carrier? Let’s analyze the functional groups present and discuss Linkerology® possibilities for permanent or trigger-inducible, tracelessly-cleavable linkage.

    read more
  5. Cell-Free Bioengineering & Linkerology®

    Bioengineering in combination with Linkerology®. Check out the unique options for membrane proteins, recombinant immunotoxins (RITs) and novel antibody-drug conjugates.

    read more
  6. Conjugating Natural Products (3)

    The potential of natural products of daily life, such as 6-shogaol from ginger (Zingiber officinale), can flourish if the active ingredient is conjugated to an appropriate carrier via Linkerology®. 

    read more
  7. Functionalization of Carbon Materials by Linker Attachment

    Allotropes of carbon show distinct characteristics in structure and e.g. electric and biophysiological properties. Discover how these materials can be further exploited by linker attachment!

    read more
  8. Functionalization of (Inert) Polymeric Surfaces

    Plasma technology allows to equip inert polymers such as poly(ethylene) or polystyrene with functional groups like amine or carboxylate enabling further conjugations and applications. Read on!

    read more
  9. Conjugating Natural Products (2)

    Infinite like the deep sea – marine natural products are an infinite source of (bio)active compounds. In this series we present how natural products can be conjugated to empower their inherent potential.

    read more
  10. Conjugating Natural Products (1)

    From evolution to solution - natural products are an infinite source of (bio)active compounds. In this series we present how natural products can be conjugated to empower their inherent potential.

    read more

Items 1-10 of 47

Page
Show per page