Hydrazone Resins

Hydrazone Resins

Hydrazone resins provide a new and convenient method for the synthesis of peptide hydrazides and thus for peptide thio esters, which can be applied during ligation techniques and glycosilation.

It was shown that the hydrazone linker is completely stable in the course of standard Fmoc SPPS. Moreover, it can tolerate a treatment with 5% TFA/DCM thus permitting selective removal of Mtt or related acid-labile protecting groups. Subsequent application of cleavage cocktails containing net TFA permits to obtain the desired peptides in a reasonable yields and purity.

  1. Structure image for Fmoc-NHN=Pyv Resin
    Fmoc-NHN=Pyv Resin

    Product code: PYV1000

    Particle size : 100-200 mesh

  2. Structure image for Fmoc-L-Ala-NHN=Pyv Resin
    Fmoc-L-Ala-NHN=Pyv Resin

    Product code: PYV1100

    Particle size : 100-200 mesh

  3. Structure image for Fmoc-L-Arg(Pbf)-NHN=Pyv Resin
    Fmoc-L-Arg(Pbf)-NHN=Pyv Resin

    Product code: PYV1110

    Particle size : 100-200 mesh

  4. Structure image for Fmoc-L-Asn(Trt)-NHN=Pyv Resin
    Fmoc-L-Asn(Trt)-NHN=Pyv Resin

    Product code: PYV1120

    Particle size : 100-200 mesh

  5. Structure image for Fmoc-L-Asp(OtBu)-NHN=Pyv Resin
    Fmoc-L-Asp(OtBu)-NHN=Pyv Resin

    Product code: PYV1130

    Particle size : 100-200 mesh

  6. Structure image for Fmoc-L-Cys(Trt)-NHN=Pyv Resin
    Fmoc-L-Cys(Trt)-NHN=Pyv Resin

    Product code: PYV1140

    Particle size : 100-200 mesh

  7. Structure image for Fmoc-L-Glu(tBu)-NHN=Pyv Resin
    Fmoc-L-Glu(tBu)-NHN=Pyv Resin

    Product code: PYV1150

    Particle size : 100-200 mesh

  8. Structure image for Fmoc-L-Gln(Trt)-NHN=Pyv Resin
    Fmoc-L-Gln(Trt)-NHN=Pyv Resin

    Product code: PYV1160

    Particle size : 100-200 mesh

  9. Structure image for Fmoc-Gly-NHN=Pyv Resin
    Fmoc-Gly-NHN=Pyv Resin

    Product code: PYV1170

    Particle size : 100-200 mesh

  10. Structure image for Fmoc-L-His(Trt)-NHN=Pyv Resin
    Fmoc-L-His(Trt)-NHN=Pyv Resin

    Product code: PYV1180

    Particle size : 100-200 mesh

  11. Structure image for Fmoc-L-Ile-NHN=Pyv Resin
    Fmoc-L-Ile-NHN=Pyv Resin

    Product code: PYV1190

    Particle size : 100-200 mesh

  12. Structure image for Fmoc-L-Leu-NHN=Pyv Resin
    Fmoc-L-Leu-NHN=Pyv Resin

    Product code: PYV1200

    Particle size : 100-200 mesh

  13. Structure image for Fmoc-L-Lys(Boc)-NHN=Pyv Resin
    Fmoc-L-Lys(Boc)-NHN=Pyv Resin

    Product code: PYV1210

    Particle size : 100-200 mesh

  14. Structure image for Fmoc-L-Met-NHN=Pyv Resin
    Fmoc-L-Met-NHN=Pyv Resin

    Product code: PYV1220

    Particle size : 100-200 mesh

  15. Structure image for Fmoc-L-Phe-NHN=Pyv Resin
    Fmoc-L-Phe-NHN=Pyv Resin

    Product code: PYV1230

    Particle size : 100-200 mesh

  16. Structure image for Fmoc-L-Pro-NHN=Pyv Resin
    Fmoc-L-Pro-NHN=Pyv Resin

    Product code: PYV1240

    Particle size : 100-200 mesh

  17. Structure image for Fmoc-L-Ser(tBu)-NHN=Pyv Resin
    Fmoc-L-Ser(tBu)-NHN=Pyv Resin

    Product code: PYV1250

    Particle size : 100-200 mesh

  18. Structure image for Fmoc-L-Thr(tBu)-NHN=Pyv Resin
    Fmoc-L-Thr(tBu)-NHN=Pyv Resin

    Product code: PYV1260

    Particle size : 100-200 mesh

  19. Structure image for Fmoc-L-Trp(Boc)-NHN=Pyv Resin
    Fmoc-L-Trp(Boc)-NHN=Pyv Resin

    Product code: PYV1270

    Particle size : 100-200 mesh

  20. Structure image for Fmoc-L-Tyr(tBu)-NHN=Pyv Resin
    Fmoc-L-Tyr(tBu)-NHN=Pyv Resin

    Product code: PYV1280

    Particle size : 100-200 mesh

  21. Structure image for Fmoc-L-Val-NHN=Pyv Resin
    Fmoc-L-Val-NHN=Pyv Resin

    Product code: PYV1290

    Particle size : 100-200 mesh