Drug Delivery

  1. (Functionalized) Fullerenes of Versatile Value

    Iris Biotech presents (functionalized) fullerenes of different core size (C60 vs. C70) as versatile tools for multiple functionalization. Read more about their unique properties and fields of applications.

    read more
  2. Polyarginine

    Polyarginines are well known for their ability to enhance cell penetration.

    read more
  3. Poly(L-Glutamic Acid)

    Poly-(α-L-glutamic acid) is a synthetic polypeptide of L-Glu linked by the alpha-amino groups (α-PGA). These polyanionic and biodegradable polymers can be used for a variety of purposes.

    read more
  4. Polylysines

    Polylysines are polymers of the canonical amino acid Lysine, and are characterized by their high charge density caused by the presence of one free amino group per lysine monomer.

    read more
  5. Mercapto-PEG-Acids for Bioconjugation

    Mercapto-PEG-Acids are highly hydrophilic, non-antigenic, non-immunogenic and non-toxic.

    read more
  6. 1st Generation Click Chemistry

    Azido and alkyne functions can cyclise by an intramolecular CuI or Cu0 catalyzed azide-alkyne 1,3-dipolar cycloaddition (CuAAC). This so-called Click Reaction, developed by K. Barry Sharpless and Morton Meldal, has meanwhile grown to a widely used type of reaction orthogonal to many other types of reactions in different kinds of applications.

    read more
  7. 2nd Generation Click Chemistry

    read more
  8. Recombinant Incorporation of Amino Acids into Proteins

    Mutant or modified aminoacyl tRNA synthetases (aaRS) have been used to charge non-natural amino acids to the corresponding tRNA, which incorporates them into polypeptides or proteins during recombinant synthesis.

    read more
  9. Peptide Structure Stabilization by Click Chemistry

    As Boc and Fmoc protected derivatives of both azido and alkyne amino acids are available, they can be introduced into peptide sequences through standard SPPS protocols, for example. In an α-helical secondary structure amino acids at positions i and i+4 are above each other.

    read more
  10. Azido-Masked Amino Function

    read more

Items 1-10 of 29

Page
Show per page