News

Visit this regularly updated section to check out the latest additions to our portfolio, as well as the latest developments at Iris Biotech.

  1. Thiol-reactive Linkers for ADCs

    The thiosuccinimide linkage is a prominent connective motif resulting from the reaction of a thiol and an alkyl maleimide. Read on to learn more about its applications and potential improvements.

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  2. Product of the Month: Fluorescent SARS-CoV-2 Protease Substrates

    Mpro is a key enzyme of coronaviruses (coronaviridae) and thus an attractive drug target. Iris Biotech offers fluorescent substrates, which can be used to perform various types of screenings and to identify potential inhibitors of COVID-19.

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  3. Deamino- and Decarboxy-Histidine Derivatives

    Interested in histidine derivatives? Iris Biotech provides a selection of deamino- and decarboxy-products. Find out more about benefits and potential applications of our new building blocks.

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  4. Fighting SARS-CoV-2

    Fighting COVID-19 by modifying essential viral proteins via glycation through methylglyoxal – a reactive carbonyl compound known from the Maillard reaction. Read on to find out more!

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  5. Product of the Month: Imatinib And Other Linked Kinase Inhibitor Analogues

    Iris Biotech offers various linked kinase inhibitors including analogues of Gefitinib, Imatinib, Sunitinib, Staurosporine and many more, which can easily be conjugated to other biomolecules, if desired. Have a look and read more.

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  6. Valine-Citrulline Based Enzymatically Cleavable Linkers

    Iris Biotech presents its selection of Val-Cit-based linkers, a dipeptide motif frequently utilized for the development of ADCs with increased serum stability and high cleavage efficiency.

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  7. Nitrodibenzofuran (NDBF) based Photocleavable Protecting Groups

    Nitrodibenzofuran (NDBF) is a photocleavable side chain protecting group that can be removed by photolysis upon irradiation with UV-light or – especially for in vivo applications – by two-photon excitation using near infrared light.

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  8. (Functionalized) Fullerenes of Versatile Value

    Iris Biotech presents (functionalized) fullerenes of different core size (C60 vs. C70) as versatile tools for multiple functionalization. Read more about their unique properties and fields of applications.

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  9. Product Focus: Next Generation Phosphoamino Acid Analogs

    Iris Biotech presents the next-generation of hydrolysis-stable phosphono-analogs of pSer, pThr and pTyr. Fluorination renders the phosphonic acid more acidic and thus an even better mimic of the parent phosphoamino acid.

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  10. Product Focus: Arginine Derivatives

    Looking to optimize or functionalize your peptide? Explore our ever-growing selection of Arg derivatives and find the one suitable for your application.

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