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Resins
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ChemMatrix® Discontinued
The ChemMatrix® resin production and distribution was discontinued by its manufacturer SEQENS. Products are only available at Iris till current stock is sold out. Read on for more information!
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Process Development of SPPS
From mg synthesis of a peptide up to bulk quantities often makes a huge difference in the route of production. Read on for more information about Iris Biotech’s process development services.
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Resins for Solid Phase Peptide Synthesis (Part 2)
You want to get an overview about the various resins available at Iris Biotech as well as their specifications, differences, and applications? Read on for further information and details.
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Resins for Solid Phase Peptide Synthesis (Part 1)
You just started working in the field of solid phase (peptide) synthesis and want to get familiar with resins? Click here to get an overview about the different parameters describing resins.
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PotM: Towards “Greener” Peptide Synthesis – Alternative Solvents for Loading of 2-CTC and 4-MBH-Br
Replace undesired solvents such as DCM, THF and DMF during the loading of 2-CTC and 4-MBH-Br resin by a “greener” EtOAc/MeCN (1:1) mixture. Click here and read on for more details.
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Hydrazone Resins as Alternative to SEA Resins
Discover the versatile applications of hydrazone resins e.g. for the preparation of peptide hydrazides, or the generation of peptide thio esters. Read on to find out more and see our available products.
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Phase change during peptide synthesis. Application of Fmoc-Rink Amide Linker on 2-Chlorotrityl Resin
Abstract: A symposium report. Protected peptides were synthesized using 9-fluorenylmethoxycarbonyl (Fmoc) amino acids and the acid labile 2-chlorotrityl and the multidetachable 2-chlorotrityl-Rink-linker resins.
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NEW Hydrazone Resin
A new hydrazone resin enables a convenient way to synthesize peptide hydrazides for Hydrazone Ligation Technique and Native Chemical Ligation (NCL).
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4-Methylbenzhydryl-Resins - the Better Wang-Resin alternative
Wang resins are widely used for peptide synthesis. However, certain side reactions, like diketopiperazin formation limit their use. 4-Methylbenzhydryl resin needs more space and leaves less room for this type of side reactions. Standard “Wang-typical” Fmoc/tBu coupling protocols can be applied.
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Convenient method of peptide hydrazide synthesis using a new hydrazone resin
Peptide hydrazides can be easily synthesized using a new hydrazone resin, obtained via acylation of aminomethyl polystyrene by Fmoc-hydrazone of pyruvic acid.
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