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PEG spacers eliminate the common issues of aggregation with biotinylated proteins, oligonucleotides, antibodies, and other biological materials. They provide optimal avidin/streptavidin binding, because the PEG spacer makes the biotin freely available for streptavidin in the capture/binding step. Biotin-PEG Reagents are very water soluble, eliminate non-specific binding and are non-antigenic and nonimmunogenic. They increase significantly signal to noise ratio in analytical applications.
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