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Resins - Polymeric carriers are the solid support for carrying out solid phase organic and particularly peptide synthesis. Depending on the solvents applied hydrophobic polymers derived from polystyrene and hydrophilic ones can be used, in order to cover the full chemical space of possible reaction conditions. For convenience in peptide synthesis resins are already preloaded with appropriate amino acids. This technology spreads out into different applications, like for the production of peptide thio esters used in native chemical ligation or in other organic synthesis applications serving with immobilized reagents or scavenging impurities, side products or excess of educts.