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H-Aeg(Fmoc)-OMe*HCl
Chemical name: N-[2-(9-Fluorenylmethyloxycarbonyl)-amino)-ethyl]glycine methylester hydrochloride // Synonyms: Fmoc-Aeg-OMe, Fmoc-Aeg-OMe.HCl, Methyl [2-(Fmoc-amino)ethylamino]acetate hydrochloride, N-[2-(Fmoc-amino)-ethyl]glycine methylester hydrochloride, 156939-69-4 net, methyl(2-((((9H-fluoren-9-yl)metho xy)carbonyl)amino)ethyl)glycinate
- Product code:HAA9275
- CAS No.:172405-43-5
- Formula:C20H22N2O4*HCl
- Molecular weight:354.41*36.45 g/mol
- Purity :min. 99%
Starting at $106.25
description
Building block for preparation of Fmoc-protected PNA (Peptide Nucleic Acid) monomers.
This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis.
references
On the Necessity of Nucleobase Protection for 2-Thiouracil for Fmoc-Based Pseudo-Complementary Peptide Nucleic Acid Oligomer Synthesis; R. H. E. Hudson, A. Heidari, T. Martin-Chan, G. Park, J. A. Wisner; J. Org. Chem. 2019; 84(21): 13252-13261. https://doi.org/10.1021/acs.joc.9b00821.
A Practical and Efficient Approach to PNA Monomers Compatible with Fmoc-Mediated Solid-Phase Synthesis Protocols; A. Porcheddu, G. Giacomelli, I. Piredda, M. Carta, G. Nieddu; Eur. J. Org. Chem. 2008; 34: 5786-5797. https://doi.org/10.1002/ejoc.200800891.
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