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H-L-Sec(oNB)-OH*HCl
Chemical name: (R)-2-amino-3-((2-nitrobenzyl)selanyl)propanoic acid // Synonyms: H-Sec(oNB)*HCl, o-Nitrobenzyl selenocysteine hydrochloride
- Product code:HAA9465
- CAS No.:324582-23-2 net
- Formula:C10H12N2O4Se*HCl
- Molecular weight:303.18*36.46 g/mol
- Purity :min.99,0%
Starting at $285.00
description
Photocaged unnatural amino-acid that can be incorporated into proteins for site-specific protein modifications. Selenocysteine is decaged by UV-irradiation.
references
Evaluation of the Kinetics of β-Elimination Reactions of Selenocysteine Se-Conjugates in Human Renal Cytosol: Possible Implications for the Use as Kidney Selective Prodrugs; M. Rooseboom, N. P. E. Vermeulen, I. Andreadou, J. N. Commandeur; J. Pharmacol. Exp. Ther. 2000; 294(2): 762-769.
Tissue distribution of cytosolic β-elimination reactions of selenocysteine Se-conjugates in rat and human; M. Rooseboom, N. P. E. Vermeulen, E. J. Groot, J. N. M. Commandeur; Chem.-Biol. Interact. 2002; 140(3): 243-264. https://doi.org/10.1016/S0009-2797(02)00039-X
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