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Product of the month
Herein we highlight products which we consider to be of special interest to our customers.
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Lysine Dendrons
We now offer a series of Lysine dendrons for chemoselective functionalization of molecules containing carbonyl groups. These multivalent molecules carry diverse types of moieties, such as amine- or hydroxyl-groups, DOTA chelators or triphenylphosphonium (TPP) cations.
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PEG-Conjugates of Folic Acid and Cholesterol
Conjugates of PEG and folic acid or cholesterol, respectively, combine the positive properties of these molecules. Those conjugates are available with a wide variety of functional groups and different PEG chain lengths to suit your needs.
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Inexpensive & High Quality Guanylation Reagents
We now offer N,N'-Bis-Boc-N"-triflylguanidine, at both a very competitive price and our habitual high quality. Find out about the usefulness of this and our other guanylation reagents!
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New Substituted Ornithine Derivatives
l-Ornithine derivative containing peptides play important roles in SAR studies, enzyme inhibition and cancer research. We now offer a variety of Nδ-substituted ornithines containing heterocyclic, aromatic and aliphatic groups, as well as N-substituted C3- and C4-analogs of ornithine.
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NGlyO – for beta sheet formation
Surprising behavior of NXO-peptides.
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It is a significant property of peptides that oxalo-retro azapeptides have the same donor and acceptor distances and properties for hydrogen bridge formation as a tripeptide fragment and therefore induce beta-sheet formation at this position.
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NEW Hydrazone Resin
A new hydrazone resin enables a convenient way to synthesize peptide hydrazides for Hydrazone Ligation Technique and Native Chemical Ligation (NCL).
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Stable Conjugation with Thiols
Maleimide (MAL) reacts rather specific with free thiol groups and forms appropriate conjugates. However, this reaction is slightly reversible, resulting in loss of the conjugation partner.
Amino functions open the maleimido ring structure through hydrolysis with nucleophilc neighboring effect and thus inhibit the undesired release reaction.
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Polar Amino Acids for Increased Solubilization
alpha-Sulfo-beta-Alanine has been used to couple to hydrophobic molecules and peptides and increase solubility. Attachment can be carried out by conventional Fmoc/tBu protocols.
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Custom Synthesis of Alkyne Amino Acids Analogues for Click Conjugation
1,4-substituted 1,2,3-triazole are isosteric to peptide bonds and result in peptide mimetics which even retain activity e.g. in case of certain tyrosinease inhibitors.
We offer custom synthesis of Alkyne Amino Acid Analogues as building blocks for triazol formation via Click conjugation. Side chains can represent all natural amino acids or unusual residues. In combination with our alpha-azido acids we can offer the whole range of building blocks to design Click-peptide bond analogues for every proteinogenic amino acid.
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Luciferin for Research and Industry – from MG to KG Scale
In modern biotechnology there are numerous applications for the luminogenic luciferase assay. We supply luciferin from mg scale for research applications like monitoring of gene expression or tumor growth up to kg quantities for hygiene surveillance in food industry
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