Product of the month

Herein we highlight products which we consider to be of special interest to our customers.

1. News Product of the month Life Sciences

   23/01/2013

   Coelenterazines – very versatile Luminophores

   A prominent luciferase group was first discovered in Coelenterata and the corresponding light emitting molecule was therefore named coelenterazine.

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2. News Product of the month Amino Acids

   13/11/2012

   2-(Fmoc-amino)-3-azidobutanoic acid

   Building Blocks for the synthesis of 2,3-diaminobutanoic acid containing peptides or for Click reactions.

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3. News Product of the month Linkerology

   13/02/2012

   Azido-Spermine for Click Chemistry

   Spermines and other Biogenic Polyamines
   interact due to their multi cationic structure with DNA!

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4. News Product of the month Life Sciences

   13/02/2012

   MiDye550-Alkyne

   Properties of the MiDye Chromophore System:

   • Readily applicable to biolabelling, Click 
     conjugation protocols and peptide synthesis
   • Stable under buffer conditions (pH 4-8) 
     and in solid phase peptide synthesis
   • Broadly applied in cell und animal 
     imaging, tested in FRET systems
   • Available in larger quantities compared 
     to e.g. Alexa, Cy-Dyes etc.
   • Purities > 85%, supplied as freeze-dried solid powder

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5. News Product of the month Amino Acids

   10/11/2011

   Alpha-Sulfo-beta-Alanine

   alpha-Sulfo-beta-Alanine has been used to couple to hydrophobic labels like Cyanine and Rhodamine dyes and other hydrophobic residues to increase their solubility in water. As di- or tripeptide a further increase of hydrophilicity can be achieved. Fmoc-beta-Ala(SO3H)-OH can be coupled in SPPS by standard phosphonium or uronium based coupling reagents. In high throughput technologies for DNA sequencing and genomics charge-modified dye-labeled dideoxynucleoside-5’-triphosphates were synthesized for ‘direct-load’ applications in DNA sequencing.

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6. News Product of the month Drug Delivery

   09/11/2011

   Cross-Linker: Mal-AMCHC-OSu

   Mal-AMCHC-OSu

   trans-N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate

   Formula:                    C16H18N₂O₆
   Molecular Weight:     334,33 g/mole

   CAS:  64987-85-5

   CODE:  MAA1000
   

   1g:       EUR    300,-    US$   420,-
   5g:       EUR  1200,-    US$ 1680,-

   Prices are in EUR, net, exw Germany, shipping not include

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7. News Product of the month Reagents

   09/11/2011

   Troc-OSu

   Reported applications:

   Introduction of 9-fluorenylmethyloxycarbonyl, trichloroethoxycarbonyl, and benzyloxycarbonyl amine protecting groups into O-unprotected hydroxylamino acids using succinimidyl carbonates; Anelka Paquet; Can. J. Chem.; 1982; 60: 976.

   Widely Applicable Deprotection Method of 2,2,2-Trichloroethoxycarbonyl (Troc) Group Using Tetrabutylammonium Fluoride; Cheng-yuan Huanga; Ning Wanga; Katsumasa Fujikia; Yuji Otsukaa; Masao Akamatsua; Yukari Fujimotoa; Koichi Fukasea; Journal of Carbohydrate Chemistry 2010; 29(6): 289 – 298.

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8. News Product of the month Reagents

   09/11/2011

   DTT (Cleland's Reagent)

   Cleland's reagent, also known as dithiothreitol or DTT is a water soluble protective reagent for sulfhydryl groups.
   It reduces disulfide linkages to free sulfhydryl groups in proteins and enzymes.
   It is a component of buffers used in protocols for the isolation and purification of proteins.

   DTT (racemic), Cleland's Reagent

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9. News Product of the month Life Sciences

   09/11/2011

   Actiplus-CALB

   Lipase B from Candida antarctica (EC 3.1.1.3)
   adsorbed on hydrophobic polymer Polystyrene DVB cross linked, 300-700µm,
   Synthetic Activity >10.000 U/g (dry), 
   very high mechanical stability - suitable for packed bed reactors

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10. Product of the month

    09/11/2011

    4-Azido-L-homoalanine

    H-L-Aha-OH*HCl
    H-L-Dab(N3)-OH

    4-Azido-L-homoalanine
    (S)-2-Amino-4-azidobutanoic acid hydrochloride

    Formula:                    C4H8N₄O₂*HCl
    Molecular Weight:     144,13*35,45 g/mole

    CAS:  942518-29-8

    CODE:  HAA5730
    

    1g:       EUR    200,-    US$    300,- 
    5g:       EUR    800,-    US$  1200,-

    Prices are in EUR, net, exw Germany, shipping not include

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