Fmoc-4-AMCHC-OH

Chemical name: trans-4-(9-Fluorenylmethyloxycarbonylaminomethyl)-cyclohexanoic acid // Synonyms: Fmoc-tranexamic acid, trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid, Fmoc-4-Amc-OH, Fmoc-Trx-OH

Product code:FAA1647
CAS No.:167690-53-1
Formula:C23H25NO4
Molecular weight:379,46 g/mol
Grouped product items
Qty Packing unit Price SKU
5 g
$74.25
FAA1647.0005
25 g
$243.00
FAA1647.0025
100 g
$742.50
FAA1647.0100
Safety Data Sheets
description

Fmoc-AMCHC is used as a linker in solid-phase peptide synthesis to construct various biologically active conjugates. This fragment is present in many Antibody-Drug Conjugates (Kadcyla®, IMMU-132).

references

Benesova, Martina; Bauder-Wuest, Ulrike; Schaefer, Martin; Klika, Karel D.; Mier, Walter; Haberkorn, Uwe; Kopka, Klaus; Eder, Matthias; J. Med. Chem. 2016; 59(5): 1761-1775. DOI:10.1021/acs.jmedchem.5b01210;

Behrens et al PCT Int. Appl. (2011), WO 2011089255 A1.

Zhu et al PCT Int. Appl. (2019), WO 2019011166 A1.


Bulk or large quantity order?

Do you need larger quantities for your development or production?

Do you need further information of this product?

get in contact

Quick contact

Please send me more information about

We found other products you might like!
Structure image for Boc-1,4-trans-ACHA-OH
Boc-1,4-trans-ACHA-OH

Starting at Please inquire

Structure image for Fmoc-TOAC-OH
Fmoc-TOAC-OH

Starting at $162.00

Structure image for Boc-1,4-cis-ACHA-OH
Boc-1,4-cis-ACHA-OH

Starting at Please inquire

Structure image for Z-1,4-cis-ACHA-OH
Z-1,4-cis-ACHA-OH

Starting at Please inquire

Structure image for Boc-4-AMCHC-OH
Boc-4-AMCHC-OH

Starting at $74.25

Structure image for Fmoc-1,4-trans-ACHA-OH
Fmoc-1,4-trans-ACHA-OH

Starting at $121.50

Structure image for Fmoc-4-AMCHC-OH
Fmoc-4-AMCHC-OH

Starting at $74.25

Structure image for Fmoc-1,4-cis-ACHA-OH
Fmoc-1,4-cis-ACHA-OH

Starting at $135.00

Structure image for HOOC-trans-Cyclohexane-COOMe
HOOC-trans-Cyclohexane-COOMe

Starting at $236.25

Structure image for (Boc)2-4-trans-GCHC-OH
(Boc)2-4-trans-GCHC-OH

Starting at $109.35

Structure image for N3-trans-MCHC-OH
N3-trans-MCHC-OH

Starting at $148.50

Structure image for (Boc-NH-THP)acetic acid
(Boc-NH-THP)acetic acid

Starting at $256.50

Structure image for Boc-NH-cis-cyclooctane-COOH
Boc-NH-cis-cyclooctane-COOH

Starting at $567.00

Structure image for Boc-NH-cis-cycloheptane-COOH
Boc-NH-cis-cycloheptane-COOH

Starting at $526.50

Structure image for (Fmoc-NH-cyclohexyl)acetic acid
(Fmoc-NH-cyclohexyl)acetic acid

Starting at Please inquire

Structure image for (Fmoc-NH-cycloheptyl)acetic acid
(Fmoc-NH-cycloheptyl)acetic acid

Starting at Please inquire

Structure image for (Fmoc-NH-cyclooctyl)acetic acid
(Fmoc-NH-cyclooctyl)acetic acid

Starting at Please inquire

Structure image for (Fmoc-NH-THP)acetic acid
(Fmoc-NH-THP)acetic acid

Starting at $580.50

Structure image for Fmoc-NH-cis-cyclooctane-COOH
Fmoc-NH-cis-cyclooctane-COOH

Starting at $661.50

Structure image for Fmoc-NH-cis-cyclooct-3-ene-1-COOH
Fmoc-NH-cis-cyclooct-3-ene-1-COOH

Starting at Please inquire

Structure image for Fmoc-NH-cis-2-Me-cyclohexane-COOH
Fmoc-NH-cis-2-Me-cyclohexane-COOH

Starting at Please inquire

Structure image for Fmoc-NH-cis-cycloheptane-COOH
Fmoc-NH-cis-cycloheptane-COOH

Starting at Please inquire

Structure image for Fmoc-NH-cis-cyclooct-4-ene-COOH
Fmoc-NH-cis-cyclooct-4-ene-COOH

Starting at Please inquire

Structure image for 8-Aminocyclooct-4-ene-COOH (S,R)
8-Aminocyclooct-4-ene-COOH (S,R)

Starting at Please inquire

Structure image for (1-Aminocyclooctyl)acetic acid
(1-Aminocyclooctyl)acetic acid

Starting at Please inquire

Structure image for (4-Amino-THP)acetic acid
(4-Amino-THP)acetic acid

Starting at Please inquire

Structure image for (4-Amino-THP)acetic acid*HCl
(4-Amino-THP)acetic acid*HCl

Starting at $297.00

Structure image for 2-Aminocyclooctane-COOH (S,R/R,S)
2-Aminocyclooctane-COOH (S,R/R,S)

Starting at Please inquire

Structure image for 2-Aminocyclooct-3-ene-COOH (S,R/R,S)
2-Aminocyclooct-3-ene-COOH (S,R/R,S)

Starting at Please inquire

Structure image for (1-Aminocyclohexyl)acetic acid
(1-Aminocyclohexyl)acetic acid

Starting at Please inquire

Structure image for 2-Amino-2-Me-cyclohexane-COOH (R,S)
2-Amino-2-Me-cyclohexane-COOH (R,S)

Starting at Please inquire

Structure image for 2-Aminocycloheptane-COOH (R,S)
2-Aminocycloheptane-COOH (R,S)

Starting at Please inquire

Structure image for Fmoc-4-APipAc-OH
Fmoc-4-APipAc-OH

Starting at $236.25

Structure image for Boc-Cep-OH
Boc-Cep-OH

Starting at $675.00

Structure image for Boc,Me-AMCHC
Boc,Me-AMCHC

Starting at $101.25

Structure image for Fmoc,Me-AMCHC
Fmoc,Me-AMCHC

Starting at $195.75

Structure image for Boc-1-aminomethyl-THP-COOH
Boc-1-aminomethyl-THP-COOH

Starting at Please inquire

Structure image for Fmoc-4-aminomethyl-THP-COOH
Fmoc-4-aminomethyl-THP-COOH

Starting at Please inquire

Structure image for Fmoc-Cmpi-OH
Fmoc-Cmpi-OH

Starting at Please inquire

Structure image for Fmoc-Acp-OH*2HCl
Fmoc-Acp-OH*2HCl

Starting at Please inquire

Structure image for Fmoc-L-Lys(Heptanoyl)-OH
Fmoc-L-Lys(Heptanoyl)-OH

Starting at $94.50

Structure image for Fmoc-L-Lys(Hexanoyl)-OH
Fmoc-L-Lys(Hexanoyl)-OH

Starting at $94.50

Structure image for Fmoc-ThpGly-OH
Fmoc-ThpGly-OH

Starting at $202.50

Structure image for Fmoc-ThtpGly-OH
Fmoc-ThtpGly-OH

Starting at $405.00