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Chemical name: 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)tetrahydro-2H-pyran-4-carboxylic acid // Synonyms: Fmoc-4-amino-tetrahydropyran-4-carboxylic acid, Fmoc-4-amino-THP-4-COOH
|Molecular weight:||367,40 g/mol|
This tetrahydropyran substituted glycine can be used as building block to extend the chemical diversity of peptidic compounds and screen for improved pharmaceutical properties in the search for new lead structures.
Cyclic peptide compound having Kras inhibiting action, and pharmaceutical composition; M. Tanada, K. Takano, A. Matsuo, M. Tamiya, Y. Chiyoda, T. Ito, T. Iida; 2021; WO 2021090855 A1.
Preparation of resin-bound cyclic quaternary amino acids; D. Dhanos; 2002; WO 2002046128 A2.
Preparation of amino acid derivatives as probes for drug discovery; A. M. M. Mjalli, C. Wysong, J. Baudry, T. S. Yokum, R. Andrews, W. K. Banner; US 20030125315 A1.
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