Fmoc-L-Nva(3-Et)-OH

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-3-ethyl-L-norvaline // Synonyms: (S)-Fmoc-2-amino-3-ethyl-pentanoic acid, (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-ethylpentanoic acid

Product code:FAA5360
CAS No.:1310680-47-7
Formula:C22H25NO4
Molecular weight:367,44 g/mol
Grouped product items
Qty Packing unit Price SKU
1 g
$472.50
FAA5360.0001
5 g
$1,890.00
FAA5360.0005
Safety Data Sheets
New
references

Discovery of Begacestat, a Notch-1-Sparing g-Secretase Inhibitor for the Treatment of Alzheimer’s Disease. S. C. Mayer, A. F. Kreft, B. Harrison, M. Abou-Gharbia, M. Antane, S. Aschmies, K. Atchison, M. Chlenov, D. C. Cole, T. Comery, G. Diamantidis, J. Ellingboe, K. Fan, R. Galante, C. Gonzales, D. M. Ho, M. E. Hoke, Y. Hu, D. Huryn, U. Jain, M. Jin, K. Kremer, D. Kubrak, M. Lin, P. Lu, R. Magolda, R. Martone, W. Moore, A. Oganesian, M. N. Pangalos, A. Porte, P. Reinhart, L. Resnick, D. R. Riddell, J. Sonnenberg-Reines, J. R. Stock, S.-C. Sun, E. Wagner, T. Wang, K. Woller, Z. Xu, M. M. Zaleska, J. Zeldis, M. Zhang, H. Zhou, and J. S. Jacobsen; J. Med. Chem. 2008; 51: 7348-7351. https://doi.org/10.1021/jm801252w.

Synthesis and structure-activity relationship of a novel series of heterocyclic sulfonamide g-secretase inhibitors. J. Pu, A. F. Kreft, S. H. Aschmies, K. P. Atchison, J. Berkowitz, T. J. Caggiano, M. Chlenov, G. Diamantidis, B. L. Harrison, Y. Hu, D. Huryn. J. S. Jacobsen, M. Jin, K. Lipinski. P. Lu. R. L. Martone, K. Morris, J. Sonnenberg-Reines, D. R. Riddell, J. Sabalski, S.-C. Sun, E. Wagner, Y. Wang, Z. Xu, H. Zhou, and L. Resnick; Bioorg. Med. Chem. 2009; 17: 4708-4717. https://doi.org/10.1016/j.bmc.2009.04.052.

Structure-activity relationships of tubulysin analogues. J. R. Courter, J. Z. Hamilton, N. R. Hendrick, M. Zaval, A. B. Waight, R. P. Lyon, P. D. Senter, S. C. Jeffrey, and P. J. Burke; Bioorg. Med. Chem. Lett. 2020; 30: 127241. https://doi.org/10.1016/j.bmcl.2020.127241.

Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity. S. J. Middendorp, J. Wilbs, C. Quarroz, S. Calzavarini, A. Angelillo-Scherrer, and C. Heinis; J. Med. Chem. 2017; 60: 1151-1158. https://doi.org/10.1021/acs.jmedchem.6b01548.

Structure-activity relationship study of the tumour-targeting peptide A20FMDV2 via modification of Lys16, Leu13, and N- and/or C-terminal functionality. K.-y. Hung, P. W. R. Harris, A. Desai, J. F. Marshall, and M. A. Brimble; Eur. J. Med. Chem. 2017; 136: 154-164. https://doi.org/10.1016/j.ejmech.2017.05.008.

Lead Optimization Yields High Affinity Frizzled 7-Targeting Peptides That Modulate Clostridium difficile Toxin B Pathogenicity in Epithelial Cells. S. Hansen, A. H. Nile, S. C. Mehta, J. Fuhrmann, and R. N. Hannoush; J. Med. Chem. 2019; 62: 7739-7750. https://doi.org/10.1021/acs.jmedchem.9b00500.

Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2-P4 study. M. J. Ang, Q. Y. Lau, F. M. Ng, S. W. Then, A. Poulsen, Y. K. Cheong, Z. X. Ngoh, Y. W. Tan, J. Peng, T. H. Keller, J. Hill, J. J. Chu, and C. S. B. Chia; J. Enzyme Inhib. Med. Chem. 2016; 3: 332-339. https://doi.org/10.3109/14756366.2015.1018245.

Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P2 position of PEXEL peptidomimetics. W. Nguyen, A. N. Hodder, R. Bestel de Lezongard, P. E. Czabotar, K. E. Jarman, M. T. O’Neill, J. K. Thompson, H. J. Sabroux, A. F. Cowman, J. A. Boddey, B. E. Sleebs; Eur. J. Med. Chem. 2018; 154: 182-198. https://doi.org/10.1016/j.ejmech.2018.05.022.


Bulk or large quantity order?

Do you need larger quantities for your development or production?

Do you need further information of this product?

get in contact

Quick contact

Please send me more information about

We found other products you might like!
Structure image for Trt-L-Hnv-OH*DEA
Trt-L-Hnv-OH*DEA

Starting at Please inquire

Structure image for Fmoc-L-Nva-OH
Fmoc-L-Nva-OH

Starting at $81.00

Structure image for Boc-L-Hnv(Bzl)-OH*DCHA
Boc-L-Hnv(Bzl)-OH*DCHA

Starting at $459.00

Structure image for H-L-Nva-OH
H-L-Nva-OH

Starting at $87.75

Structure image for Boc-L-Nva-OH
Boc-L-Nva-OH

Starting at $108.00

Structure image for Trt-D-Hnv-OH*DEA
Trt-D-Hnv-OH*DEA

Starting at Please inquire

Structure image for Z-L-Nva-OH
Z-L-Nva-OH

Starting at $101.25

Structure image for H-alpha-Tfm-L-Nva-OH
H-alpha-Tfm-L-Nva-OH

Starting at Please inquire

H-D-Nva-OH
H-D-Nva-OH

Starting at Please inquire

Structure image for Fmoc-Nnva-OH
Fmoc-Nnva-OH

Starting at $155.25

Structure image for Boc-L-Nva(3-Et)-OH
Boc-L-Nva(3-Et)-OH

Starting at $472.50

Structure image for H-D-Nva(5,5,5-F3)-OH
H-D-Nva(5,5,5-F3)-OH

Starting at Please inquire

Structure image for H-D-Abu(4,4,4-F3)-OH
H-D-Abu(4,4,4-F3)-OH

Starting at Please inquire

Structure image for H-D-Nva-OtBu*HCl
H-D-Nva-OtBu*HCl

Starting at $364.50

Structure image for Boc-L-TfNva-OH
Boc-L-TfNva-OH

Starting at Please inquire

Structure image for Fmoc-L-TfNva-OH
Fmoc-L-TfNva-OH

Starting at Please inquire

Structure image for Boc-L-4,4-DfNva-OH
Boc-L-4,4-DfNva-OH

Starting at Please inquire

Structure image for Fmoc-L-4,4-DfNva-OH
Fmoc-L-4,4-DfNva-OH

Starting at Please inquire

Structure image for Boc-D-Nva(3-Et)-OH
Boc-D-Nva(3-Et)-OH

Starting at $540.00

Structure image for Fmoc-D-Nva(3-Et)-OH
Fmoc-D-Nva(3-Et)-OH

Starting at $540.00

Structure image for Boc-L-Nva(3-Et-3-Me)-OH
Boc-L-Nva(3-Et-3-Me)-OH

Starting at $1,080.00

Structure image for Fmoc-L-Nva(3-Et-3-Me)-OH
Fmoc-L-Nva(3-Et-3-Me)-OH

Starting at $1,080.00