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Fmoc-L-Nva(3-Et-3-Me)-OH

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)- 3-ethyl-3-methyl-L-norvaline // Synonyms: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-ethyl-3-methylpentanoic acid, Fmoc-3-ethyl-3-methyl-L-norvaline, Fmoc-3-ethyl-3-methyl-Nva, Fmoc-3-ethyl-3-methyl-L-Nva, Fmoc-Nva(3-Et-3-Me)-OH

Product code:FAA8500
Formula:C23H27NO4
Molecular weight:381,47 g/mol
Grouped product items
Qty Packing unit Price SKU
1 g
$877.50
FAA8500.1000
5 g
$2,160.00
FAA8500.5000
New
description

Iris Biotech offers various Nva derivatives with different sterical and electronical properties, which can be incorporated into peptides for the investigation of structure activity relationships and lead optimization. Furthermore, Norvaline and its derivatives can be incorporated into peptides as surrogate for Methionine in order to prevent oxidation of Met.


references

Scaleable catalytic asymmetric Strecker syntheses of unnatural alpha-amino acid; S. J. Zuend, M. P. Coughlin, M. P. Lalonde, E. N. Jacobsen; Nature 2009: 461(7266): 968-70. https://doi.org/10.1038/nature08484.

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