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H-L-Lys(oNB)-OH*HCl
Chemical name: N6-(((2-nitrobenzyl)oxy)carbonyl)-L-lysine // Synonyms: H-L-Lys(2-NO2-Z), H-Lys(oNB)*HCl, ONBK, H-L-Lys(oNB)-OH*HCl, H-L-Lys(2-nitrobenzyloxycarbonyl) hydrochloride, o-nitrobenzyl-oxycarbonyl-N-epsilon-L-lysine hydrochloride,N-epsilon-(o-nitrobenzyloxyca rbonyl)-L-lysine, Net CAS: 750556-72-0
- Product code:FAA9345
- CAS No.:228564-76-9
- Formula:C14H19N3O6*HCl
- Molecular weight:325.32*36.45 g/mol
- Purity :min. 98.0%
Starting at $120.00
description
Photocaged Lysine derivative that can be incorporated into proteins. The photolabile group of ONBK can be efficiently removed by 365 nm light to afford a free lysine residue.
references
A Facile System for Encoding Unnatural Amino Acids in Mammalian Cells; P. R. Chen, D. Groff, J. Guo, W. Ou, S. Cellitti, B. H. Geierstanger, P. G. Schultz; Angew. Chem. Int. Ed. 2009; 48(22): 4052-4055. https://doi.org/10.1002/anie.200900683
Site-Specific Engineering of Chemical Functionalities on the Surface of Live Hepatitis D Virus; S. Lin, H. Yan, L. Li, M. Yang, B. Peng, S. Chen, W. Li, P. R. Chen; Angew. Chem. Int. Ed. 2013; 52(52): 13970-13974. https://doi.org/10.1002/anie.201305787
Mechanism-Based Design of a Photoactivatable Firefly Luciferase; J. Zhao, S. Lin, Y. Huang, J. Zhao, P. R. Chen; J. Am. Chem. Soc. 2013; 135(20): 7410-7413. https://doi.org/10.1021/ja4013535
Spatiotemporal functional assembly of split protein pairs through a light-activated SpyLigation; E. R: Ruskowitz, B. G. Munoz-Robles, A. C. Strange, C. H. Butcher, S. Kurniawan, J. R. Filteau, C. A. DeForest; Nature Chem. 2023; 15: 694-704. https://doi.org/10.1038/s41557-023-01152-x
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