Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying though a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.Continue to Iris Biotech GmbHSend request to US distributor
Chemical name: 2-(1-hydroxy-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentylidene)-5,5-dimethylcyclohexane-1,3-dione
Starting at $162.50
This cleavable linker is highly valuable for usage in protein enrichment and other applications. A linker based on the Dde protecting group leads to efficient release of targets under mild aqueous buffered conditions with 2% hydrazine.
Cleavable trifunctional biotin reagents for protein labelling, capture and release; Y. Yang and S. H. Verhelst; Chem Commun (Camb) 2013; 49: 5366-8. https://doi.org/10.1039/c3cc42076k
Versatile Dde-based primary amine linkers for solid phase synthesis; S. R. Chhabra, A. N. Khan, B. W. Bycroft; Tetrahedron Lett. 1998; 39: 3585-3588. https://doi.org/10.1016/S0004-4039(98)00555-3
Mapping the Binding Site of BMS-708163 on gamma-Secretase with Cleavable Photoprobes; N. Gertsik, C. W. Am Ende, K. F. Geoghegan, C. Nguyen, P. Mukherjee, S. Mente, U. Seneviratne, D. S. Johnson and Y. M. Li; Cell Chem Biol 2017; 24: 3-8. https://doi.org/10.1016/j.chembiol.2016.12.006
Transient affinity tags based on the Dde protection/deprotection strategy: Synthesis and application of 2-biotinyl-and 2-hexanoyldimedone; B. Kellam, W. C. Chan, S. R. Chhabra, B. W. Bycroft; Tetrahedron Lett. 1997; 38(30): 5391-5394. https://doi.org/10.1016/S0040-4039(97)01180-5
Comprehensive mapping of O-GlcNAc modification sites using a chemically cleavable tag; M. E. Griffin, E. H. Jensen, D. E. Mason, C. L. Jenkins, S. E. Stone, E. C. Peters and L. C. Hsieh-Wilson; Mol. BioSyst. 2016; 12: 1756-1759. https://doi.org/10.1039/C6MB00138F
Do you need larger quantities for your development or production?
Please send me more information about