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Life Sciences
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PotM: Argpyrimidine Building Block for SPPS
Argpyrimidine is the result of a Maillard Reaction-like nonenzymatic posttranslational modification. You want to investigate the effect of this change on function and stability? Get the building block!
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Choose your Taste – Functionalized Halo/Snap/Clip Substrates
The HaloTag®, SNAP-Tag® and CLIP-TagTM represent versatile tools for the specific, covalent attachment of in principle any molecule of choice to a protein of interest. Discover our substrates!
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PotM: His Tags for the Chemical Modification of Peptides
Jensen et al. developed two methods that use poly-His sequences to direct the highly selective acylation of proteins, either at the N-terminus or at a specific Lys residue. Read on for more information.
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DTT and Spermidine for RNA Buffers and Vaccine Production
See how our “mRNA grade” DTT and Spermidine can support also your nucleic acid production. Read on for more information.
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PotM: Biotin – Desthiobiotin - Iminobiotin
Herein, we present 2-Iminobiotin, a cyclic guanidino analogue of biotin with pH-dependent affinity for avidin, and compare it to biotin and desthiobiotin. Click here for more detailed information.
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Photoswitches
Photoswitches grant the ability to modulate the function of a molecule by effecting a structural change upon irradiation with UV light. Find out about our photoswitchable building blocks and their properties.
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Dyes and Fluorescent Labels at Iris Biotech
Dyes and fluorescent labels are an invaluable tool for diagnostics, medical and biochemical research. Iris Biotech offers labels with excitation ranges from UV to near-IR and various functional groups.
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PotM: Proteolysis Targeting Chimeras (PROTACs®)
Drug the undruggable – click here to get more information about the use of PROteolysis TArgeting Chimeras (PROTACs®) as a tool for targeted protein degradation and discover available building blocks.
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Isotopically Labeled Drugs
Stable isotopically labeled drugs are routinely used to investigate a drug’s metabolism, distribution, bioavailability, side effects and potential toxicity. Discover our selection of labeled drugs.
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PotM: Substrates for Fusion (Halo/Snap/Clip)-Tagged Proteins
Discover our selection of substrates for Halo-, Snap-, and Clip-tagged proteins bearing different terminal groups suitable for further functionalization, e.g. biotinylation and Click chemistry.
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