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Chemical name: N-(17-mercapto-15-oxo-4,7,10-trioxa-14-azaheptadecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
|Molecular weight:||534,73 g/mol|
This biotin derivative bears a terminal sulfhydryl moiety. It can be used to prepare various biotinylated conjugates. Biotin can be subsequently detected e.g. via streptavidin or avidin. The PEG linker improves the overall solubility of the derivative.
Preparation of Biomolecule Microstructures and Microarays by Thiol-ene Photoimmobilization; D. Weinreich, M. Köhn, P. Jonkheijm, U. Westerlink, L. Dehmelt, H. Engelkamp, P. C. M. Christianen, J. Kuhlmann, J. C. Maan, D. Nüsse, H. Schröder, R. Wacker, E. Voges, R. Breinbauer, H. Kunz, C. M. Niemeyer, H. Waldmann; ChemBioChem 2010; 11(2): 235-247. https://doi.org/10.1002/cbic.200900559.
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